PTH/PTHr receptor; PTH/PTHrP type I receptor; PTHR1; Parathyroid hormone/parathyroid hormone-related peptide receptor precursor;
Categories
Primary Antibodies
Clonality
polyclonal
Description
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.Pranay C. Patel, Arch Otolaryngol Head Neck Surg, May 1998; 124: 559. Atul A. Gawande, Arch Surg, Apr 2006; 141: 381 - 384. Timothy M. Murray, Endocr. Rev., Feb 2005; 26: 78 - 113. W. M. Philbrick, Physiol Rev, Jan 1996; 76: 127.
Host
Rabbit
Immunogen
Synthesized peptide derived from Human Parathyroid Hormone antibody.
Involvement In Disease
Hypoparathyroidism, familial isolated (FIH)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Pranay C. Patel, Arch Otolaryngol Head Neck Surg, May 1998; 124: 559. Atul A. Gawande, Arch Surg, Apr 2006; 141: 381 - 384. Timothy M. Murray, Endocr. Rev., Feb 2005; 26: 78 - 113. W. M. Philbrick, Physiol Rev, Jan 1996; 76: 127.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Parathyroid Hormone protein.
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Protein Families
Parathyroid hormone family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.