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Home / Primary Antibodies

PTCH2 Antibody (Patched 2) (R30958)

SKU : BHA17104489

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NSJ Bioreagents

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Mfr.No.	R30958
Clonality	Polyclonal
Description	PTCH2 (Patched 2), also known as PTC2, encodes a 1.203-amino acid putative transmembrane protein that is highly homologous to the PTCH product. The Patched-hedgehog signaling pathway is involved in establishing segment polarity and the anterior-posterior orientation of a number of developing appendages. The pathway is conserved from fly to vertebrates and has been implicated in a number of human neoplasms and developmental syndromes. Mutations in the human Patched gene are the basis of the nevoid basal cell carcinoma syndrome. With age, homozygous mutant male mice developed skin lesions consisting of alopecia and epidermal hyperplasia, suggesting a role for PTCH2 in adult epidermal homeostasis via Shh signaling.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of human Patched 2 (WLHDKYDTTGENLRIPP) was used as the immunogen for this PTCH2 antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Uniprot	Q9Y6C5

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the PTCH2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104489	R30958	100 ug	$419		Add to Cart

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