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Home / Antibodies

PSMC6 Antibody

SKU : BHA10558154

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA288074
Alternative Names	26S protease regulatory subunit S10B; proteasome 26S subunit ATPase 6; proteasome subunit p42; PRS10; SUG2
Categories	Primary Antibodies
Clonality	polyclonal
Description	The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.Fujiwara T., FEBS Lett. 387:184-188(1996).Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.Demartino G.N., J. Biol. Chem. 271:3112-3118(1996).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human PSMC6.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Fujiwara T., FEBS Lett. 387:184-188(1996). Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Demartino G.N., J. Biol. Chem. 271:3112-3118(1996).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total PSMC6 protein.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	P62333
Database Links	HGNC:9553 OMIM:602708 KEGG:hsa:5706 STRING:9606.ENSP00000401802 UniGene:Hs.156171
Function	Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Protein Families	AAA ATPase family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558154	CSB-PA288074	100ul	$297		Add to Cart

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