May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.Chau P. Tran, Mol. Cancer Res., Dec 2002; 1: 113. Sarajane Ross, Cancer Res., May 2002; 62: 2546 - 2553. John S. Lam, Clin. Cancer Res., Apr 2005; 11: 2591 - 2596. Robert E. Reiter, PNAS, Feb 1998; 95: 1735.
Host
Rabbit
Immunogen
Synthesized peptide derived from Human Prostate Stem Cell Antigen antibody.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.
Chau P. Tran, Mol. Cancer Res., Dec 2002; 1: 113. Sarajane Ross, Cancer Res., May 2002; 62: 2546 - 2553. John S. Lam, Clin. Cancer Res., Apr 2005; 11: 2591 - 2596. Robert E. Reiter, PNAS, Feb 1998; 95: 1735.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Prostate Stem Cell Antigen protein.
May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.
Tissue Specificity
Highly expressed in prostate (basal, secretory and neuroendocrine epithelium cells). Also found in bladder (transitional epithelium), placenta (trophoblasts), stomach (neuroendocrine cells), colon (neuroendocrine cells) and kidney (collecting ducts). Over
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.