KAP1; PRKAR1B; cAMP-dependent protein kinase type I-beta regulatory subunit;
Categories
Primary Antibodies
Clonality
polyclonal
Description
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.Solberg R., Biochem. Biophys. Res. Commun. 176:166-172(1991).Solberg R., Exp. Cell Res. 214:595-605(1994).Zhan X., Anal. Biochem. 354:279-289(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human KAP1.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Solberg R., Biochem. Biophys. Res. Commun. 176:166-172(1991). Solberg R., Exp. Cell Res. 214:595-605(1994). Zhan X., Anal. Biochem. 354:279-289(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total KAP1 protein.
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Pathway
Insulin signaling pathway
Protein Families
CAMP-dependent kinase regulatory chain family
Tissue Specificity
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.