PR domain zinc finger protein 1, also known as B Lymphocyte Induced Maturation Protein 1 (BLIMP-1), is a protein that in humans is encoded by the PRDM1 gene. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alteatively spliced transcript variants that encode different isoforms have been reported.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
A recombinant human protein corresponding to amino acids M1-Q230 was used as the immunogen for the PRDM1 / BLIMP1 antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Subcellular Location
Nuclear
Uniprot
O75626
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the BLIMP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.