This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 349-377 from the human protein was used as the immunogen for this PR antibody.
Isotype
Mouse IgM
Species Reactivity
Human
Note
Titration of the PR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P06401
Format
Ascites
Purity
Ascites
Storage
Aliquot the PR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.