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Home / Primary Antibodies

PPP1R16B Antibody

SKU : BHA10558598

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA584562
Alternative Names	TGF-beta-inhibited membrane-associated protein; hTIMAP; CAAX box protein TIMAP; Ankyrin repeat domain-containing protein 4;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.Cao W., Am. J. Physiol. 283:C327-C337(2002).Nagase T., DNA Res. 5:355-364(1998).Nakajima D., DNA Res. 9:99-106(2002).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human PPP1R16B.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells. Cao W., Am. J. Physiol. 283:C327-C337(2002). Nagase T., DNA Res. 5:355-364(1998). Nakajima D., DNA Res. 9:99-106(2002).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total PPP1R16B protein.
Subcellular Location	Cell membrane, Cell membrane, Lipid-anchor, Nucleus, Cell projection

Uniprot	Q96T49
Database Links	HGNC:15850 OMIM:613275 KEGG:hsa:26051 STRING:9606.ENSP00000299824 UniGene:Hs.45719
Function	Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558598	CSB-PA584562	100ul	$297		Add to Cart

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