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Home / Antibodies

POLL Antibody

SKU : BHA10558049

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA100387
Alternative Names	DNA polymerase lambda; EC 2.7.7.7; EC 4.2.99.-; Pol Lambda; DNA polymerase kappa
Categories	Primary Antibodies
Clonality	polyclonal
Description	Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.Aoufouchi S., Nucleic Acids Res. 28:3684-3693(2000).Nagasawa K.I., J. Biol. Chem. 275:31233-31238(2000).Ota T., Nat. Genet. 36:40-45(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human DNA Polymerase λ
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. Aoufouchi S., Nucleic Acids Res. 28:3684-3693(2000). Nagasawa K.I., J. Biol. Chem. 275:31233-31238(2000). Ota T., Nat. Genet. 36:40-45(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total DNA Polymerase λ protein.
Subcellular Location	Nucleus

Uniprot	Q9UGP5
Database Links	HGNC:9184 OMIM:606343 KEGG:hsa:27343 STRING:9606.ENSP00000299206 UniGene:Hs.523230
Function	DNA polymerase that functions in several pathways of DNA repair
Pathway	DNA repair pathway
Protein Families	DNA polymerase type-X family
Tissue Specificity	Expressed in a number of tissues. Abundant in testis.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558049	CSB-PA100387	100ul	$297		Add to Cart

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