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Home / Primary Antibodies

POLE3 Antibody / CHRAC-17 (V9234SAF)

SKU : BHA17123132

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NSJ Bioreagents

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Mfr.No.	V9234SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators. CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex), which increases the accessibility of nucleosomal DNA in an ATP-dependent manner. Unlike other known chromatin remodeling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing. This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array. In the presence of CHRAC, the nucleosomal ATPase ISWI catalyzes several ATP-dependent transitions of chromatin structure.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant full-length human DNA polymerase epsilon subunit 3 protein was used as the immunogen for the POLE3 antibody.
Isotype	Mouse IgG1
Species Reactivity	Human
Note	Optimal dilution of the POLE3 antibody should be determined by the researcher.

Uniprot	Q9NRF9

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the POLE3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	FACS, IF, IHC-P
Description	Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123132	V9234SAF-100UG	100ug	$499		Add to Cart

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