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Home / Primary Antibodies

PNPLA8 Antibody

SKU : BHA10558290

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA196783
Alternative Names	calcium-independent phospholipase A2-gamma; EC 3.1.1.5; intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2-gamma; patatin-like phospholipase domain-containing protein 8
Categories	Primary Antibodies
Clonality	polyclonal
Description	Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.Tanaka H., Biochem. Biophys. Res. Commun. 272:320-326(2000).Mancuso D.J., J. Biol. Chem. 275:9937-9945(2000).Hillier L.W., Nature 424:157-164(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human PNPLA8.
Involvement In Disease	Mitochondrial myopathy with lactic acidosis (MMLA)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. Tanaka H., Biochem. Biophys. Res. Commun. 272:320-326(2000). Mancuso D.J., J. Biol. Chem. 275:9937-9945(2000). Hillier L.W., Nature 424:157-164(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total PNPLA8 protein.
Subcellular Location	Endoplasmic reticulum membrane, Single-pass membrane protein, Golgi apparatus membrane, Single-pass membrane protein, Cytoplasm, perinuclear region

Uniprot	Q9NP80
Database Links	HGNC:28900 OMIM:251950 KEGG:hsa:50640 STRING:9606.ENSP00000257694 UniGene:Hs.617340
Function	Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.
Tissue Specificity	Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558290	CSB-PA196783	100ul	$297		Add to Cart

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