Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. It is a member of the protein kinase C (PKC) gene family. Family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Family members also serve as major receptors for phorbol esters, a class of tumor promoters. PKC beta has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. It has been found that it is activated by oxidative conditions in the cell, induces phosphorylation of <a href=../search_result.php?search_txt=shc>p66 (SHC)</a> and triggers mitochondrial accumulation of the protein after it is recognized by the prolyl isomerase <a href=../search_result.php?search_txt=pin1>PIN1</a>.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 542-671) was used as the immunogen for this PKC beta antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Gene Id
5579
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the PKC beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.