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Home / Antibodies

PINK1 Antibody

SKU : BHA17102391

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NSJ Bioreagents

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Mfr.No.	F53741
Clonality	Monoclonal
Description	PINK1 protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form. (UniProt)
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	Recombinant protein was used to produced this PINK1 antibody.
Isotype	IgG1
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Uniprot	Q9BXM7
Clone No	38CT20.8.5

Format	Ascites
Purification	Ascites
Storage	Aliquot the PINK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ELISA
Dilution	Weste blot: 1:500-1:2000,IHC (Paraffin): 1:10-1:50

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102391	F53741	0.1 ml	$389		Add to Cart

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