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Home / Primary Antibodies / Polyclonal Antibodies

PI3K p110 (alpha) antibody

SKU : BHA10806410

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Mfr.No.	FNab06418
Alternative Names	P110alpha ; PI3kinasesubunitalpha ; PI3K ; PI3Kalpha ; PI3Kp110(alpha) ; PI3-kinasep110subunitalpha ; PIK3CA ; PtdIns3kinasesubunitalpha
Background	Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4, 5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.
Categories	Primary Antibodies
Clonality	polyclonal
Description	PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB). The antibody is specific to PIK3CA.
Host	Rabbit
Immunogen	phosphoinositide-3-kinase, catalytic, alpha polypeptide
Isotype	IgG
Molecular Weight	110 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	P110 alpha, PI3 kinase subunit alpha, PI3K, PI3K alpha, PI3K p110(alpha), PI3-kinase p110 subunit alpha, PIK3CA, PtdIns 3 kinase subunit alpha

Uniprot	P42336
Gene Id	5290
Research Area	Signal Transduction
Weight	120kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, FC, IP

Description

ELISA ; WB ; IHC ; FC ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:100-1:400

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab06418.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806410	FNab06418	100ug	$240		Add to Cart

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