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Home / Primary Antibodies

Phospho-TNNI3 (Ser43) Antibody

SKU : BHA10560032

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA182407
Alternative Names	CMH7, RCM1, cTnI, CMD2A, TNNC1
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of Serine 43(K-I-S(p)-A-S) derived from Human TNNI3.
Involvement In Disease	Cardiomyopathy, familial hypertrophic 7 (CMH7); Cardiomyopathy, familial restrictive 1 (RCM1); Cardiomyopathy, dilated 2A (CMD2A); Cardiomyopathy, dilated 1FF (CMD1FF)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of TNNI3 only when phosphorylated at Serine 43.

Uniprot	P19429
Database Links	HGNC:11947 OMIM:115210 KEGG:hsa:7137 STRING:9606.ENSP00000341838 UniGene:Hs.709179
Function	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Pathway	cAMP signaling pathway Cardiac muscle contraction
Protein Families	Troponin I family

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560032	CSB-PA182407	100ul	$360		Add to Cart

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