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Home / Antibodies

Phospho-PXN (Ser178) Antibody

SKU : BHA10560209

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA057796
Alternative Names	Paxillin; PXN;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).S Chen L.B., Griffin J.D. J. Biol. Chem. 270:5039-5047(1995)Bell G.I.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of Serine 178(A-L-S(p)-P-L) derived from Human Paxillin.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). S Chen L.B., Griffin J.D. J. Biol. Chem. 270:5039-5047(1995) Bell G.I.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
Species	Homo Sapiens (Human)
Specificity	The Antibody detects endogenous levels of Paxillin only when phosphorylated at Ser178.
Subcellular Location	Cytoplasm, cytoskeleton, Cell junction, focal adhesion, Cytoplasm, cell cortex

Uniprot	P49023
Database Links	HGNC:9718 OMIM:602505 KEGG:hsa:5829 STRING:9606.ENSP00000228307 UniGene:Hs.446336
Function	Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Pathway	Chemokine signaling pathway VEGF signaling pathway Focal adhesion Regulation of actin cytoskeleton Leukocyte transendothelial migration
Protein Families	Paxillin family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560209	CSB-PA057796	100ul	$360		Add to Cart

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