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Home / Primary Antibodies

Phospho-PKA R2 Antibody / PRKAR2A (pS99) (RQ5417)

SKU : BHA17110083

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NSJ Bioreagents

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Mfr.No.	RQ5417
Clonality	Monoclonal
Description	cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by the PRKAR2A gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human PKA R2 / PRKAR2A (surrounding pS99) was used as the immunogen for the phospho-PKA R2 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P13861
Clone No	AOG-16

Format	Purified
Purification	Affinity purified
Storage	Store the phospho-PKA R2 antibody (pS99) at -20°C.

Applications	WB
Dilution	Weste blot: 1:500-1:2000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110083	RQ5417	100 ul	$419		Add to Cart

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