NeuroD Acts as a differentiation factor during neurogenesis. Transcriptional activator. Binds to the insulin gene E-box. Tamimi R., Genomics 34:418-421(1996).Yokoyama M., Brain Res. Mol. Brain Res. 42:135-139(1996).Miyachi T., Brain Res. Mol. Brain Res. 69:223-231(1999).
Host
Rabbit
Immunogen
Peptide sequence around phosphorylation site of Serine 274(P-L-S(p)-P-P) derived from Human Neuro D.
Involvement In Disease
Maturity-onset diabetes of the young 6 (MODY6); Diabetes mellitus, non-insulin-dependent (NIDDM)
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
NeuroD Acts as a differentiation factor during neurogenesis. Transcriptional activator. Binds to the insulin gene E-box.
Tamimi R., Genomics 34:418-421(1996). Yokoyama M., Brain Res. Mol. Brain Res. 42:135-139(1996). Miyachi T., Brain Res. Mol. Brain Res. 69:223-231(1999).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of Neuro D only when phosphorylated at serine 274.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.