Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.Hatakeyama M., Science 244:551-556(1989).Dunham I., Nature 402:489-495(1999).Mulloy J.C., J. Virol. 70:3599-3605(1996)
Host
Rabbit
Immunogen
Peptide sequence around phosphorylation site of tyrosine 364(Q-G-Y(p)-F-F) derived from Human IL-2Rβ/CD122 .
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.Hatakeyama M., Science 244:551-556(1989).Dunham I., Nature 402:489-495(1999).Mulloy J.C., J. Virol. 70:3599-3605(1996)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of IL-2Rβ/CD122 only when phosphorylated at tyrosine 364.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.