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Home / Primary Antibodies

Phospho-IL10RA (Ser319/323) Antibody

SKU : BHA10560294

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA949178
Alternative Names	IL10R; CDW210A; HIL-10R; IL-10R1; IL10RA
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Receptor for IL10; binds IL10 with a high affinity.Okwor I,et al. (2009) Proc Natl Acad Sci U S A.106(33):13951-6.Chen G,et al. (2009) Parasitology. 136(10):1107-20. Gonzalez P,et al.(2009) J Neuropathol Exp Neurol.68(4):391-403.
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of Serine 319/Serine 323 (D-S(p)-G-F-G-S(p)-T) derived from Human IL-10R subunit alpha.
Involvement In Disease	Inflammatory bowel disease 28 (IBD28)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Receptor for IL10; binds IL10 with a high affinity. Okwor I,et al. (2009) Proc Natl Acad Sci U S A.106(33):13951-6. Chen G,et al. (2009) Parasitology. 136(10):1107-20. Gonzalez P,et al.(2009) J Neuropathol Exp Neurol.68(4):391-403.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of IL-10R subunit alpha protein only when phosphorylated at serine 319 and serine 323.
Subcellular Location	Membrane, Single-pass type I membrane protein

Uniprot	Q13651
Database Links	HGNC:5964 OMIM:146933 KEGG:hsa:3587 STRING:9606.ENSP00000227752 UniGene:Hs.504035
Function	Receptor for IL10; binds IL10 with a high affinity.
Pathway	Jak-STAT signaling pathway
Protein Families	Type II cytokine receptor family
Tissue Specificity	Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560294	CSB-PA949178	100ul	$360		Add to Cart

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