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Home / Primary Antibodies

Phospho-ESR2 (Ser105) Antibody

SKU : BHA10560155

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA177881
Alternative Names	ESR2; ESTRB; Estrogen receptor beta; NR3A2;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.Hamilton-Burke W, et al. (2010)Am J Pathol 177, 1079-86. St-Laurent V, Sanchez M, Charbonneau C, Tremblay A (2005) J Steroid Biochem Mol Biol 94, 23-37. Tremblay A, Tremblay GB, Labrie F, Gigu篓篓re V (1999) Mol Cell 3, 513-9 .
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of serine105(Q-R-S(p)-P-W) derived from Human Estrogen Receptor- beta.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Hamilton-Burke W, et al. (2010)Am J Pathol 177, 1079-86. St-Laurent V, Sanchez M, Charbonneau C, Tremblay A (2005) J Steroid Biochem Mol Biol 94, 23-37. Tremblay A, Tremblay GB, Labrie F, Gigure V (1999) Mol Cell 3, 513-9 .
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of Estrogen Receptor- beta only when phosphorylated at serine 105.
Subcellular Location	Nucleus

Uniprot	Q92731
Database Links	HGNC:3468 OMIM:601663 KEGG:hsa:2100 STRING:9606.ENSP00000343925 UniGene:Hs.660607
Function	Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner
Pathway	Estrogen signaling pathway
Protein Families	Nuclear hormone receptor family, NR3 subfamily
Tissue Specificity	Isoform 1 is expressed in testis and ovary, and at a lower level in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, prostate, colon, bone marrow, mammary gland and uterus. Also found in uterine bone, breast, and ovarian tumor cell lines, b

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560155	CSB-PA177881	100ul	$360		Add to Cart

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