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Home / Antibodies

Phospho-DNM1 (Ser774) Antibody

SKU : BHA10560002

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA058486
Alternative Names	DNM
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of serine 774(R-R-S(p)-P-T) derived from Dynamin-1.
Involvement In Disease	Epileptic encephalopathy, early infantile, 31 (EIEE31)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of Dynamin-1 only when phosphorylated at Serine 774.
Subcellular Location	Cytoplasm, Cytoplasm, cytoskeleton

Uniprot	Q05193
Database Links	HGNC:2972 OMIM:602377 KEGG:hsa:1759 STRING:9606.ENSP00000362014 UniGene:Hs.522413
Function	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
Pathway	Oxidative Phosphorylation Phospholipase D signaling pathway Endocytosis Synaptic vesicle cycle
Protein Families	TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560002	CSB-PA058486	100ul	$360		Add to Cart

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