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Home / Antibodies

Phospho-CLDN6 (Tyr219) Antibody

SKU : BHA10560224

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA207788
Alternative Names	claudin 6; claudin-6; CLD6; Skullin 2;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Claudin 6 Plays a major role in tight junction-specific obliteration of the intercellular space. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO- 3. Keen T.J., Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.Troy T., Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.Clark H.F., Genome Res. 13:2265-2270(2003).
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of tyrosine 219 (T-K-N-Y(p)-V) derived from Human Claudin 6.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Claudin 6 Plays a major role in tight junction-specific obliteration of the intercellular space. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO- 3. Keen T.J., Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases. Troy T., Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases. Clark H.F., Genome Res. 13:2265-2270(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of Claudin 6 only when phosphorylated at tyrosine 219.
Subcellular Location	Cell junction, tight junction, Cell membrane, Multi-pass membrane protein

Uniprot	P56747
Database Links	HGNC:2048 OMIM:615798 KEGG:hsa:9074 STRING:9606.ENSP00000328674 UniGene:Hs.533779
Function	Plays a major role in tight junction-specific obliteration of the intercellular space.
Protein Families	Claudin family
Tissue Specificity	Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560224	CSB-PA207788	100ul	$360		Add to Cart

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