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Home / Antibodies

Phospho-BCR (Tyr360) Antibody

SKU : BHA10560133

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA950927
Alternative Names	BCR; BCR protein; BCR1; Breakpoint cluster region protein;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.Perazzona B, et al. (2008) Oncogene 27, 2208-14. Sun T, Campbell M, Gordon W, Arlinghaus RB (2001) Biopolymers 60, 61-75 . Wu Y, Liu J, Arlinghaus RB (1998)Oncogene 16, 141-6.
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of tyrosine 360 (T-T-Y(p)-R-M) derived from Human Bcr.
Involvement In Disease	Leukemia, chronic myeloid (CML)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity. Perazzona B, et al. (2008) Oncogene 27, 2208-14. Sun T, Campbell M, Gordon W, Arlinghaus RB (2001) Biopolymers 60, 61-75 . Wu Y, Liu J, Arlinghaus RB (1998)Oncogene 16, 141-6.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 360.
Subcellular Location	Cell junction, synapse, postsynaptic cell membrane, postsynaptic density

Uniprot	P11274
Database Links	HGNC:1014 OMIM:151410 KEGG:hsa:613 STRING:9606.ENSP00000303507 UniGene:Hs.517461
Function	GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560133	CSB-PA950927	100ul	$360		Add to Cart

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