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Home / Primary Antibodies

Phospho-ANXA2 (Ser26) Antibody

SKU : BHA10560256

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA548570
Alternative Names	Annexin A2; Annexin II; Annexin-2; CAL1H; Calpactin I heavy chain
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.Huang K.-S., Cell 46:191-199(1986).Spano F., Gene 95:243-251(1990).Bechtel S., BMC Genomics 8:399-399(2007).
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of Serine 26 (Y-G-S(p)-V-K) derived from Human ANXA2.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Huang K.-S., Cell 46:191-199(1986). Spano F., Gene 95:243-251(1990). Bechtel S., BMC Genomics 8:399-399(2007).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of ANXA2 only when phosphorylated at serine 26.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane, Melanosome

Uniprot	P07355
Gene Id	302
Database Links	HGNC:537 OMIM:151740 KEGG:hsa:302 STRING:9606.ENSP00000346032 UniGene:Hs.511605
Function	Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9
Protein Families	Annexin family
Weight	Calculated: 39kDa Observed: 39kDa

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560256	CSB-PA548570	100ul	$360		Add to Cart

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