Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.Wuellrich-Schmoll A., Eur. J. Biochem. 238:374-380(1996).van den Berg I.E.T., Am. J. Hum. Genet. 61:539-546(1997).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human KPBB.
Involvement In Disease
Glycogen storage disease 9B (GSD9B)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
Wuellrich-Schmoll A., Eur. J. Biochem. 238:374-380(1996). van den Berg I.E.T., Am. J. Hum. Genet. 61:539-546(1997).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total KPBB protein.
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.