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Home / Primary Antibodies

PEG3 Antibody

SKU : BHA10558022

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA022042
Alternative Names	Paternally-expressed gene 3 protein; Zinc finger and SCAN domain-containing protein 24; PEG3; KIAA0287; ZSCAN24
Categories	Primary Antibodies
Clonality	polyclonal
Description	Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B By similarity. Possesses a tumor suppressing activity in glioma cells.Van den Veyver I.B., J. Soc. Gynecol. Invest. 8:305-313(2001).Kohda T., Genes Cells 6:237-247(2001).Hiby S.E., Hum. Mol. Genet. 10:1093-1100(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human PEG3.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B By similarity. Possesses a tumor suppressing activity in glioma cells. Van den Veyver I.B., J. Soc. Gynecol. Invest. 8:305-313(2001). Kohda T., Genes Cells 6:237-247(2001). Hiby S.E., Hum. Mol. Genet. 10:1093-1100(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total PEG3 protein.
Subcellular Location	Nucleus, Cytoplasm

Uniprot	Q9GZU2
Database Links	HGNC:8826 OMIM:601483 KEGG:hsa:5178 STRING:9606.ENSP00000326581 UniGene:Hs.731875
Function	Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.
Protein Families	Krueppel C2H2-type zinc-finger protein family
Tissue Specificity	Brain, glial cells, astrocytes, embryo, placenta, testis, ovary and uterus. In the placenta it is found in the layer of villous cytotrophoblast cells while in the ovary it is found in the cells of the ovarian stroma including the thecal layers around the

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558022	CSB-PA022042	100ul	$297		Add to Cart

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