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PEBP1 Antibody

SKU : BHA10558572

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA948956
Alternative Names	23 kDa morphine-binding protein; B-RAF proto-oncogene serine/threonine-protein kinase; HCNP; Hippocampal cholinergic neurostimulating peptide; Neuropolypeptide h3
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor By similarity.Hori N., Gene 140:293-294(1994).Tohdoh N., Brain Res. Mol. Brain Res. 30:381-384(1995).Hochstrasser D.F., Electrophoresis 13:992-1001(1992).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human PEBP1.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor By similarity. Hori N., Gene 140:293-294(1994). Tohdoh N., Brain Res. Mol. Brain Res. 30:381-384(1995). Hochstrasser D.F., Electrophoresis 13:992-1001(1992).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total PEBP1 protein.
Subcellular Location	Cytoplasm

Uniprot	P30086
Database Links	HGNC:8630 OMIM:604591 KEGG:hsa:5037 STRING:9606.ENSP00000261313 UniGene:Hs.433863
Function	Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
Protein Families	Phosphatidylethanolamine-binding protein family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558572	CSB-PA948956	100ul	$297		Add to Cart

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