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Home / Primary Antibodies

PDCD1 Antibody / PD-1 / PD1 (V8347SAF)

SKU : BHA17127422

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NSJ Bioreagents

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Mfr.No.	V8347SAF-100UG
Clonality	Monoclonal (rat origin)
Description	PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1 mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells).
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Rat
Immunogen Region	PDCD1 transfected BHK cells were used as the immunogen for the PD1 antibody.
Isotype	Rat IgG2a, kappa
Species Reactivity	Mouse
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	Q02242

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the PD1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	Neutralization, ELISA, FACS, IF
Description	ELISA (order BSA/azide-free format for coating),Neutralization Studies (order BSA/azide-free format),Flow cytometry: 1-2ug/million cells in 0.1ml,Immunofluorescence: 0.5-1ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/pd1-antibody-rmp1-14-v8347" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127422	V8347SAF-100UG	100 ug	$499		Add to Cart

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