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Home / Antibodies

PD-L1 Antibody / B7-H1 / CD274 (R32479)

SKU : BHA17105797

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NSJ Bioreagents

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Mfr.No.	R32479
Clonality	Polyclonal
Description	Programmed death-ligand 1 (PD-L1), also known as CD274 or B7-H1, is a protein that in humans is encoded by the CD274 gene. It is mapped to 9p24.1. PD-L1 is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. It has been concluded that upregulation of PD-L1 on tumor MDCs downregulates T-cell immunity and that PD-L1 blockade may represent an approach for cancer immunotherapy. Additionally, PD-L1 can provide positive costimulatory signals for innate and adaptive immunity and for protection against intracellular bacterial infection. Whats more, it has been found that PD1/PDL1 pathway may be a good target for restoring antitumor immunity in ovarian cancer.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids F19-T238 from the mouse protein were used as the immunogen for the PD-L1 antibody.
Isotype	IgG
Predicted Reactivity	Mouse
Reactivity	Mouse
Recombinant	No

Uniprot	Q9EP73

Buffer	Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Prior to reconstitution, store at 4°C. After reconstitution, the PD-L1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, ELISA
Dilution	Weste blot: 0.1-0.5ug/ml,ELISA: 0.1-0.5ug/ml (mouse protein tested); request BSA-free format for coating

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105797	R32479	100 ug	$419		Add to Cart

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