This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alteatively spliced transcript variants encoding either the same or different isoform have been found for this gene. (provided by RefSeq).
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
This PAX6 antibody was raised using purified His-tagged recombinant human PAX6.
Isotype
Mouse IgM, k
Species Reactivity
Human
Note
Titration of the PAX6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P26367
Format
Ascites
Purity
Ascites
Storage
Aliquot the PAX6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.