May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. Eberhard D., Jimenez G., Heavey B., Busslinger M.EMBO J. 19:2292-2303(2000)
Host
Rabbit
Immunogen
Peptide sequence around aa.6~10(N-Y-P-T-P) derived from Human Pax5., Peptide sequence around aa.6~10(N-Y-P-T-P) derived from Human Pax5.
Involvement In Disease
Leukemia, acute lymphoblastic, 3 (ALL3)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
Eberhard D., Jimenez G., Heavey B., Busslinger M.EMBO J. 19:2292-2303(2000)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous level of total Pax5 protein.
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide., Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.