May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.D Fitzsimmons, Genes & Dev., Sep 1996; 10: 2198 - 2211. Hiromu Sato, J. Immunol., Apr 2004; 172: 4858 - 4865.Aline M. Morrison, Blood, Nov 1998; 92: 3865 - 3878. Gilles A. Robichaud, J. Biol. Chem., Nov 2004; 279: 49956 - 49963.
Host
Rabbit
Immunogen
Synthesized peptide derived from Human Pax-5 antibody.
Involvement In Disease
Leukemia, acute lymphoblastic, 3 (ALL3)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
D Fitzsimmons, Genes & Dev., Sep 1996; 10: 2198 - 2211. Hiromu Sato, J. Immunol., Apr 2004; 172: 4858 - 4865. Aline M. Morrison, Blood, Nov 1998; 92: 3865 - 3878. Gilles A. Robichaud, J. Biol. Chem., Nov 2004; 279: 49956 - 49963.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Pax-5 protein.
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.