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Home / Primary Antibodies

Pan Cytokeratin Antibody Cocktail (Acidic + Basic) (V3070)

SKU : BHA17113287

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NSJ Bioreagents

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Mfr.No.	V3070, V3070-20UG, V3070-100UG
Antigen	Pan Cytokeratin
Clonality	Monoclonal
Description	Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 55kDa (CK7); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 46kDa (CK17); 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	Human epidermal keratin was used as the immunogen for the pan Cytokeratin antibody cocktail.
Isotype	IgG1,kappa
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No
Subcellular Location	Cytoplasmic

Uniprot	Q7Z794, Q01546
Clone No	Cocktail PAN-CK

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the pan Cytokeratin antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	FACS, IHC-P, IF
Dilution	Flow cytometry: 0.5-1ug/million cells,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT, Immunofluorescence: 1-2ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17113287-1	V3070-20UG	20ug	$219		Add to Cart
BHA17113287-2	V3070-100UG	100ug	$499		Add to Cart

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