Rabbit Anti-Human PAK5 (pSer602) Polyclonal

Mfr.No.	SPC-1045, SPC-1045D, SPC-1045D-A390, SPC-1045D-A488, SPC-1045D-A594, SPC-1045D-BI, SPC-1045D-FITC
Immunogen Species	Human
Alternative Names	PAK 5 Antibody, PAK 7 Antibody, PAK-5 Antibody, PAK-7 Antibody, PAK5 Antibody, PAK7 Antibody, PAK7_HUMAN Antibody, Protein kinase PAK5 Antibody, Serine/threonine protein kinase PAK 7 Antibody, Serine/threonine-protein kinase PAK 7 Antibody, EC 2.7.11.1 Antibody, KIAA1264 Antibody, MGC26232 Antibody, p21 activated kinase 7 Antibody, p21 protein (Cdc42/Rac)-activated kinase 7 Antibody, p21(CDKN1A) activated kinase 7 Antibody, p21-activated kinase 5 Antibody, p21-activated kinase 7 Antibody
Categories	Antibodies
Cellular Localization	Mitochondrion, Cytoplasm, Nucleus
Certificate Of Analysis	A 1:250 dilution of SPC-1045 was sufficient for detection of PAK5 (pSer602) in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human PAK5 (pSer602) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Ser602 of human PAK5 (AA599-605), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Ser602 of human PAK5 (AA599-605)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Highly expressed in the brain.

Swissprot	Q9P286
Accession Number	NP_065074
Gene Id	57144
Target	PAK5 (pSer602)
Research Area	Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, Neurogenesis, Cancer, Apoptosis, Intracellular, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Highly expressed in the brain.
Scientific Background	PAK7 is a serine/theonine protein kinase activated by Rac/cdc42 and thus involved in regulation of cytoskeleton, cell surival and proliferation through RAF1 signalling. It phosphosphorylates BAD and prevents apoptosis. It is also involved in microtuble stablization, neurite outgrowth and development. It can destablize F-acting networks and eliminate stress fibres and focal adhesions. Pak7 expression provides a survival and could contribute to oncogenesis in this way.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 80.745 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11913626-1	SPC-1045D	Unconjugated	100 ul	$331	Add to Cart
BHA11913626-2	SPC-1045D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11913626-3	SPC-1045D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11913626-4	SPC-1045D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11913626-5	SPC-1045D-BI	Biotin	100 ul	$380	Add to Cart
BHA11913626-6	SPC-1045D-FITC	FITC	100 ul	$375	Add to Cart

PAK5 Antibody (pSer602) - SPC-1045

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