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Home / Antibodies

p65 Antibody / NF-kB (V9229SAF)

SKU : BHA17123127

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NSJ Bioreagents

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Mfr.No.	V9229SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor N B (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp B sequence in the immunoglobulin light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NF B is activated and NF B is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant full-length human RELA protein was used as the immunogen for the p65 NF-kB antibody.
Isotype	Mouse IgG2b
Species Reactivity	Human
Note	Optimal dilution of the p65 NF-kB antibody should be determined by the researcher.

Uniprot	Q04206

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the p65 NF-kB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	FACS, IF
Description	Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123127	V9229SAF-100UG	100ug	$499		Add to Cart

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