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Home / Primary Antibodies

p63 Antibody

SKU : BHA17102382

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NSJ Bioreagents

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Mfr.No.	F53705
Clonality	Monoclonal
Description	This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alteative splicing and the use of alteative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	A portion of amino acids 651-680 from the human protein was used as the immunogen for this p63 antibody.
Isotype	IgM
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q9H3D4
Clone No	603CT12.4.3

Format	Ascites
Purification	Ascites
Storage	Aliquot the p63 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Weste blot: 1:200-1:1600

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102382	F53705	0.1 ml	$379		Add to Cart

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