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Home / Antibodies

p53 Monoclonal Antibody

SKU : BHA13715080

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABM0016
Alternative Names	TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
Background	TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains.Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of TP53 and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
Clonality	Monoclonal
Description	Mouse Anti-p53 Monoclonal Antibody
Formulation	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, Liquid solution
Host	Mouse
Immunogen	Synthetic Peptide
Immunogen Region	Synthetic Peptide
Isotype	Mouse IgG1
Molecular Weight	53 KD
Others	The antibody detects endogenous p53 proteins.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	Human
Tag	Cellular tumor antigen p53
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:2000), IHC-P (1:200), IF (1:100-1:200).

Accession Number	P04637
Gene Id	7157, 7157
Research Area	Epigenetics, Cell Biology, Cancer

Concentration	1 mg/ml, 1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	WB, IF, IHC-P

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715080	ABM0016	100 uL	$229		Add to Cart

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