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Home / Primary Antibodies

Optineurin Antibody (R31756)

SKU : BHA17105123

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Mfr.No.	R31756
Clonality	Polyclonal
Description	OPTN is also known as NRP, FIP2 or HYPL. This gene encodes the coiled-coil containing protein Optineurin which may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize TNFa or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. It may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, Huntingtin, and transcription factor IIIA proteins. Alteative splicing results in multiple transcript variants encoding the same protein.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 241-577) was used as the immunogen for this Optineurin antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Uniprot	Q96CV9
Gene Id	10133

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Optineurin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, FACS
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105123	R31756	100 ug	$419		Add to Cart

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