MNUDC protein; Nuclear distribution gene C (A.nidulans) homolog; SIG-92;
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a role in neurogenesis and neuronal migration By similarity. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.Miller B.A., Exp. Hematol. 27:742-750(1999).Matsumoto N., Hum. Genet. 104:498-504(1999).Wiemann S., Genome Res. 11:422-435(2001).
Host
Rabbit
Immunogen
Synthesized non-phosphopeptide derived from Human NudC around the phosphorylation site of serine 326 (D-F-S(p)-K-A).
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Plays a role in neurogenesis and neuronal migration By similarity. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
Protein Families
NudC family
Tissue Specificity
Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.