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Home / Primary Antibodies

Nucleophosmin Antibody / NPM1 (V7607IHC)

SKU : BHA17126787

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NSJ Bioreagents

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Mfr.No.	V7607IHC-7ML
Clonality	Monoclonal (mouse origin)
Description	The protein encoded by the NPM1 gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. (RefSeq)
Formulation	Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; For IHC use only
Host	Mouse
Immunogen Region	A portion of amino acids 185-287 from the human protein was used as the immunogen for the NPM antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P06748

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the NPM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/npm-antibody-nlpp1-1-v7607" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17126787	V7607IHC-7ML	7 ml	$499		Add to Cart

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