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Home / Antibodies

NSE Antibody / Neuron Specific Enolase (V8361)

SKU : BHA17117964

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NSJ Bioreagents

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Mfr.No.	V8361, V8361-20UG, V8361-100UG
Antigen	NSE
Clonality	Monoclonal
Description	This monoclonal antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas.It it be usually employed in combination with other markers such as Synaptophysin,Chromogranin A, and Neurofilament.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	A portion of amino acids 416-433 from the human protein was used as the immunogen for the NSE antibody.
Isotype	IgG1,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic

Uniprot	P09104
Clone No	ENO2/2706

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the NSE antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	ELISA, IHC-P
Dilution	ELISA: Use Ab at 2-4ug/ml for coating; order Ab without BSA,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17117964-1	V8361-20UG	20ug	$219		Add to Cart
BHA17117964-2	V8361-100UG	100ug	$499		Add to Cart

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