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Home / Primary Antibodies

NRL Antibody

SKU : BHA10558533

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA933723
Alternative Names	Neural retina-specific leucine zipper protein; NRL; D14S46E;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor which regulates the expression of several rod-specific genes, in cluding RHO and PDE6B By similarity.Swaroop A., Proc. Natl. Acad. Sci. U.S.A. 89:266-270(1992).Farjo Q., Genomics 45:395-401(1997).Heilig R., Nature 421:601-607(2003)
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human NRL.
Involvement In Disease	Retinitis pigmentosa 27 (RP27); Retinal degeneration autosomal recessive clumped pigment type (RDCP)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Transcription factor which regulates the expression of several rod-specific genes, in cluding RHO and PDE6B By similarity. Swaroop A., Proc. Natl. Acad. Sci. U.S.A. 89:266-270(1992). Farjo Q., Genomics 45:395-401(1997). Heilig R., Nature 421:601-607(2003)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total NRL protein.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	P54845
Database Links	HGNC:8002 OMIM:162080 KEGG:hsa:4901 STRING:9606.ENSP00000380193 UniGene:Hs.652297
Function	Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B
Protein Families	BZIP family
Tissue Specificity	Expressed in the brain and the retina (PubMed:11477108). Expressed strongly in rod and cone cells (at protein level) (PubMed:11477108).

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558533	CSB-PA933723	100ul	$297		Add to Cart

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