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Home / Antibodies

NR1I3 Antibody

SKU : BHA10557922

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA586225
Alternative Names	CAR; Constitutive androstane receptor; Orphan nuclear receptor MB67; Orphan nuclear receptor NR1I3;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.Baes M., Mol. Cell. Biol. 14:1544-1552(1994).Choi H.S., J. Steroid Biochem. Mol. Biol. 56:23-30(1996).Xu R.X., Mol. Cell 16:919-928(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human NR1I3.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. Baes M., Mol. Cell. Biol. 14:1544-1552(1994). Choi H.S., J. Steroid Biochem. Mol. Biol. 56:23-30(1996). Xu R.X., Mol. Cell 16:919-928(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total NR1I3 protein.
Subcellular Location	Nucleus, Cytoplasm, Cytoplasm, cytoskeleton

Uniprot	Q14994
Database Links	HGNC:7969 OMIM:603881 KEGG:hsa:9970 STRING:9606.ENSP00000356958 UniGene:Hs.349642
Function	Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Protein Families	Nuclear hormone receptor family, NR1 subfamily
Tissue Specificity	Predominantly expressed in liver.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557922	CSB-PA586225	100ul	$297		Add to Cart

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