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Home / Primary Antibodies

NOTCH4 Antibody (R30929)

SKU : BHA17104465

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Mfr.No.	R30929
Clonality	Polyclonal
Description	NOTCH4 is a member of the Notch family. In situ hybridization revealed that Notch4 transcripts are primarily restricted to endothelial cells in embryonic and adult life, suggesting a specific role for the protein during development of vertebrate endothelium. The sequences of the mouse and human proteins are 82% identical. Northe blot analysis revealed that NOTCH4(S) is the major transcript and is expressed in a wide variety of tissues. Fluorescence in situ hybridization confirmed the location of the gene at chromosome 6p21.3. In linkage disequilibrium mapping of the MHC region in 80 British parent-offspring trios, Wei and Hemmings(2000) found that NOTCH4 was highly associated with schizophrenia. Repression of Notch4 resolved ataxia and reversed the disease progression, demonstrating that it is not only sufficient to induce but also required to sustain the disease.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of human NOTCH4 (DVAHQRNHWDLLTL) was used as the immunogen for this NOTCH4 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q99466

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the NOTCH4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104465	R30929	100 ug	$419		Add to Cart

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