140 kDa nucleolar phosphoprotein; HCV NS5A trans-regulated protein 13; HCV NS5A-transactivated protein 13; Hepatitis C virus NS5A-transactivated protein 13; KIAA0035
Categories
Primary Antibodies
Clonality
polyclonal
Description
Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.Pai C.-Y., J. Cell Sci. 108:1911-1920(1995).Ying Z.L., Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.Deloukas P., Nature 429:375-381(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human NOLC1.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.
Pai C.-Y., J. Cell Sci. 108:1911-1920(1995). Ying Z.L., Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases. Deloukas P., Nature 429:375-381(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total NOLC1 protein.
Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.