Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is mapped to 1p13.2. This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
Host
Rabbit
Immunogen Region
Recombinant human protein (amino acids S122-D186) was used as the immunogen for the NGFB antibody.
Isotype
Rabbit IgG
Reactivity
Human
Recombinant
No
Uniprot
P01138
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format
Antigen affinity purified
Purification
Antigen affinity purified
Storage
After reconstitution, the NGFB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Applications
WB, Direct ELISA
Dilution
Western blot: 1-2ug/ml,Direct ELISA: 0.1-0.5ug/ml
Reviews of NGF Antibody / Beta Nerve Growth Factor (RQ6782)