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Home / Antibodies

NFYA Antibody

SKU : BHA10557828

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA288741
Alternative Names	CAAT-box DNA binding protein subunit A; CBF-A; CBF-B; CCAAT-binding transcription factor subunit B; HAP2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.Li X.-Y., Nucleic Acids Res. 20:1087-1091(1992).Mungall A.J., Nature 425:805-811(2003).Becker D.M., Proc. Natl. Acad. Sci. U.S.A. 88:1968-1972(1991).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human NFYA.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. Li X.-Y., Nucleic Acids Res. 20:1087-1091(1992). Mungall A.J., Nature 425:805-811(2003). Becker D.M., Proc. Natl. Acad. Sci. U.S.A. 88:1968-1972(1991).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total NFYA protein.
Subcellular Location	Nucleus

Uniprot	P23511
Database Links	HGNC:7804 OMIM:189903 KEGG:hsa:4800 STRING:9606.ENSP00000345702 UniGene:Hs.10441
Function	Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.
Pathway	Antigen processing and presentation
Protein Families	NFYA/HAP2 subunit family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557828	CSB-PA288741	100ul	$297		Add to Cart

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