NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. (UniProt)
Formulation
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host
Mouse
Immunogen Region
A human recombinant protein was used as the immunogen for this NFKB1 antibody.
Isotype
Mouse IgG1
Species Reactivity
Human
Note
The stated application concentrations are suggested starting points. Titration of the NFKB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.