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Home / Antibodies

Neurofibromin Antibody / NF1 (RQ6749)

SKU : BHA17119162

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NSJ Bioreagents

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Mfr.No.	RQ6749
Cellular Localization	cytoplasmic, Nuclear
Clonality	Polyclonal (rabbit origin)
Description	Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alteatively spliced transcript variants encoding different isoforms have also been described for this gene.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids R160-Q270) was used as the immunogen for the Neurofibromin antibody.
Isotype	Rabbit IgG
Reactivity	Human, Mouse, Rat
Recombinant	No

Uniprot	P21359

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the Neurofibromin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, FACS
Dilution	Weste blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119162	RQ6749	100ug	$419		Add to Cart

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